Sickle Cell Disease Consensus Statement

Foreword and Introduction

PART I: Disease-Modifying Therapy

1. Hydroxyurea

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_{Published 2025}

2. Transfusion

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_{Published 2015}

PART II: Preventing and Managing Complications of Sickle Cell Disease

1. Chronic Pain

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^{Published 2025}

2. Acute Chest Syndrome

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^{Published 2015}

3. Fever

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_{Published 2015}

4. Stroke and Neurological Complications

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_{Published 2015}

5. Eye Complications

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_{Published 2015}

6. Pulmonary Hypertension and Pulmonary Disease

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_{Published 2015}

7. Cardiac Complications

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_{Published 2015}

8. Splenic Sequestration

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_{Published 2015}

9. Renal Complications

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_{Published 2026}

10. Priapism

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_{Published 2015}

11. Bone Complications

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_{Published 2015}

12. Skin Ulcers

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_{Published 2015}

13. Growth and Endocrine Complications

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_{Published 2015}

14. Iron Overload

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_{Published 2015}

15. Venous Thromboembolism

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_{Published 2025}

PART III: Comprehensive Care

1. Peri-operative Management

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_{Published 2015}

2. Contraception, Pre-conception Counseling and Pregnancy

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_{Published 2025}

3. Newborn Screening

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_{Published 2015}

4. Immunizations and Antimicrobial Prophylaxis

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_{Published 2015}

5. Nutritional Management

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_{Published 2015}

6. Hematopoietic Stem Cell Transplantation

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_{Published 2015}

7. Transition of Care in Adolescents and Young Adults

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_{Published 2015}

8. Comprehensive Care Centres: Creating a Canadian Network

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_{Published 2015}